Organic diet intervention significantly reduces urinary pesticide levels in U

science diet urinary

Organic diet intervention significantly reduces urinary pesticide levels in U.S. children and adults


Diet is a primary source of pesticide exposure.

Organic diet reduced neonicotinoid, OP, pyrethroid, 2,4-D exposure in U.S. families.

Greatest reduction observed for malathion, clothianidin, and chlorpyrifos.


Previous diet intervention studies indicate that an organic diet can reduce urinary pesticide metabolite excretion; however, they have largely focused on organophosphate (OP) pesticides. Knowledge gaps exist regarding the impact of an organic diet on exposure to other pesticides, including pyrethroids and neonicotinoids, which are increasing in use in the United States and globally.

To investigate the impact of an organic diet intervention on levels of insecticides, herbicides, and fungicides or their metabolites in urine collected from adults and children.

We collected urine samples from four racially and geographically diverse families in the United States before and after an organic diet intervention (n = 16 participants and a total of 158 urine samples).

We observed significant reductions in urinary levels of thirteen pesticide metabolites and parent compounds representing OP, neonicotinoid, and pyrethroid insecticides and the herbicide 2,4-D following the introduction of an organic diet. The greatest reductions were observed for clothianidin (− 82.7%; 95% confidence interval [95% CI]: − 86.6%, − 77.6%; p

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